Zhenghong Lee, Ph.D.

Zhenghong Lee, Ph.D.

Professor, Radiology and Biomedical Engineering
Courses: EBME 410

Focus Areas: Molecular imaging with a specialty in PET imaging with small molecule radio-tracers

Dr. Zhenghong Lee is a professor of Radiology and Biomedical Engineering at Case Western Reserve University and a co-leader of Cancer Imaging Program at Case Comprehensive Cancer Center. He is stationed within the Nuclear Medicine Division of the Radiology Department at University Hospitals Cleveland Medical Center. Dr. Lee has been working with SPECT and PET imaging for cancer research involving prostate cancer and hepatocellular carcinoma (HCC). He is familiar with optimal study design. Dr. Lee is an expert in multi-modal image registration and quantitative image analysis that includes compartment modeling using dynamically acquired PET image data. Dr. Lee is also well-versed in quantitative analysis and can contribute to the processing of dynamically acquired PET image data for correlation with histological evaluation. Over the years, he has gained considerable experience in animal imaging using micro-scanners for small animals such as mice and rats, and clinical scanners for mid- and large-size animals such as rabbits, woodchucks, canines, and pigs. Cancer imaging is the main research focus of his lab, as they have been investigating the mechanisms of tracer uptake in tumors as well as evaluating the potential for clinical utility of these tracers. His lab has also been developing novel reporter systems to study biology events associated with stem cell-based repair and regeneration in vivo.

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